<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="research-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">Asian Pac Isl Nurs J</journal-id><journal-id journal-id-type="publisher-id">apinj</journal-id><journal-id journal-id-type="index">43</journal-id><journal-title>Asian/Pacific Island Nursing Journal</journal-title><abbrev-journal-title>Asian Pac Isl Nurs J</abbrev-journal-title><issn pub-type="epub">2373-6658</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v9i1e74900</article-id><article-id pub-id-type="doi">10.2196/74900</article-id><article-categories><subj-group subj-group-type="heading"><subject>Short Paper</subject></subj-group></article-categories><title-group><article-title>The Effect of Using Virtual Reality on School-Age Children&#x2019;s and Caregivers&#x2019; Anxiety in the Emergency Room: True Experimental Study</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Karujan</surname><given-names>Enjelita</given-names></name><degrees>PCNS</degrees><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Wanda</surname><given-names>Dessie</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Apriyanti</surname><given-names>Efa</given-names></name><degrees>MSc</degrees><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>Faculty of Nursing, Universitas Indonesia</institution><addr-line>Gedung Pendidikan dan Laboratorium, Jl. Prof. Dr. Bahder Djohan</addr-line><addr-line>Depok</addr-line><country>Indonesia</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Ahn</surname><given-names>Hyochol</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Nurhaeni</surname><given-names>Nani</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Dhillon</surname><given-names>Reshvinder</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Dessie Wanda, PhD, Faculty of Nursing, Universitas Indonesia, Gedung Pendidikan dan Laboratorium, Jl. Prof. Dr. Bahder Djohan, Depok, 16424, Indonesia, 62 85695180195; <email>dessie@ui.ac.id</email></corresp></author-notes><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>26</day><month>8</month><year>2025</year></pub-date><volume>9</volume><elocation-id>e74900</elocation-id><history><date date-type="received"><day>24</day><month>03</month><year>2025</year></date><date date-type="rev-recd"><day>23</day><month>06</month><year>2025</year></date><date date-type="accepted"><day>25</day><month>06</month><year>2025</year></date></history><copyright-statement>&#x00A9; Enjelita Karujan, Dessie Wanda, Efa Apriyanti. Originally published in the Asian/Pacific Island Nursing Journal (<ext-link ext-link-type="uri" xlink:href="https://apinj.jmir.org">https://apinj.jmir.org</ext-link>), 26.8.2025. </copyright-statement><copyright-year>2025</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Asian/Pacific Island Nursing Journal, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://apinj.jmir.org">https://apinj.jmir.org</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://apinj.jmir.org/2025/1/e74900"/><abstract><sec><title>Background</title><p>Being treated in an emergency room (ER) could be a stressful experience and trigger anxiety in children. Virtual reality (VR) is a technology-based distraction technique that can be used for school-age children.</p></sec><sec><title>Objective</title><p>In this study, we aimed to identify the effect of using VR in reducing anxiety in school-age children in the ER and identify the relationship between caregivers&#x2019; and school-age children&#x2019;s anxiety.</p></sec><sec sec-type="methods"><title>Methods</title><p>This study employed a true experimental design using a post-test-only control group involving 66 children aged 6&#x2010;12 years, randomly selected according to the inclusion and exclusion criteria. The intervention group, consisting of 33 children, received VR intervention, and the control group, consisting of 33 children, received standard care. Three respondents dropped out. Data analysis employed descriptive statistics, independent <italic>t</italic> tests, one-way ANOVA, and Pearson correlation analysis.</p></sec><sec sec-type="results"><title>Results</title><p>Most respondents were boys (39/66, 61.9%), accompanied by their mother (34/63, 54%), and had prior experience admitted to the ER (31/63, 49.2%). The anxiety in school-age children in the intervention group (mean 17.71, SD 3.013) was lower than that in the control group (mean 22.31, SD 3.167). There was a significant difference in the anxiety mean scores between the intervention group and the control group (<italic>t</italic><sub>(61)</sub>=&#x2212;5.907, <italic>P</italic>&#x003C;.001). The mean (SD) of the caregivers&#x2019; anxiety in the intervention and control groups were 46.06 (9.413) and 54.44 (9.112), respectively. There was a moderate relationship between caregivers&#x2019; and school-age children&#x2019;s anxiety <italic>(r</italic>=.532, <italic>P</italic>&#x003C;.001).</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>This study has proven that VR can reduce school-age children&#x2019;s anxiety.</p></sec></abstract><kwd-group><kwd>anxiety</kwd><kwd>caregivers</kwd><kwd>children</kwd><kwd>emergency room</kwd><kwd>virtual reality</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>Being admitted to the emergency room could be a stressful experience and could cause anxiety in children and their families [<xref ref-type="bibr" rid="ref1">1</xref>]. When entering the emergency room, children had unpleasant experiences due to the bright lights, unusual sounds, different smells, strangers, and busy environments [<xref ref-type="bibr" rid="ref2">2</xref>]. A study showed that 77.4% of school-age children being treated in the emergency department experienced anxiety [<xref ref-type="bibr" rid="ref3">3</xref>]. Nursing interventions, such as distraction techniques, are needed to reduce anxiety and improve comfort for children. Distraction is a non-pharmacological technique that can be used to reduce anxiety in children that is easy to implement and effective in reducing anxiety [<xref ref-type="bibr" rid="ref4">4</xref>].</p><p>VR is one of the distraction techniques where children are given goggles and a headset to view a virtual display from a computer [<xref ref-type="bibr" rid="ref5">5</xref>]. A study conducted on 142 children aged 7&#x2010;12 years who received venipuncture showed that VR was effective in reducing children&#x2019;s anxiety [<xref ref-type="bibr" rid="ref6">6</xref>]. This result is in line with the results of research conducted on 40 children aged 6&#x2010;12 years who will undergo abdominal surgery, which showed that VR was effective in reducing preoperative anxiety levels [<xref ref-type="bibr" rid="ref7">7</xref>].</p><p>Watching a video using VR involves more than one sense, vision, and hearing, making VR more attractive to hold on children&#x2019;s attention compared to other techniques that only involve one sense, such as music (hearing) or picture books (vision) [<xref ref-type="bibr" rid="ref8">8</xref>]. The presence of parents can be a source of motivation and can strengthen children [<xref ref-type="bibr" rid="ref9">9</xref>]; therefore, parents&#x2019; anxiety relates to children&#x2019;s anxiety [<xref ref-type="bibr" rid="ref10">10</xref>]. In light of this, a study about the use of VR to reduce anxiety in school-age children treated in emergency rooms is needed.</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Study Design</title><p>This study was a true experiment study using a post-test-only control group design.</p></sec><sec id="s2-2"><title>Sample</title><p>This study involved 66 children aged 6&#x2010;12 years, with urgent and non-urgent triage, compos mentis (conscious), no respiratory or circulatory emergencies, no disturbance in the head and face area, and being able to communicate. The sample size was calculated using the sample size formula for hypothesis testing of the means of two independent populations based on literature [<xref ref-type="bibr" rid="ref11">11</xref>]. The effect size was 3,4 based on previous research [<xref ref-type="bibr" rid="ref12">12</xref>]. Samples were selected using simple random sampling by applying one drawing for each day of admission.</p></sec><sec id="s2-3"><title>Instrument</title><p>The instruments used were the demographic questionnaire, the short form of the Chinese version of the State Anxiety Scale for Children (CSAS-C) [<xref ref-type="bibr" rid="ref13">13</xref>] to measure children&#x2019;s anxiety, and the State Anxiety Inventory (SAI) [<xref ref-type="bibr" rid="ref14">14</xref>] to measure caregivers&#x2019; anxiety.</p></sec><sec id="s2-4"><title>Intervention</title><p>After passing the triage assessment, respondents in the intervention group received a VR intervention for 10 minutes. They watched an animated video of Pororo the Little Penguin about the situation in the emergency room. The tool used was entry-level, low-immersive VR (smartphone and headset Sinecon VR Box).</p></sec><sec id="s2-5"><title>Data Collection</title><p>Data collection for this study was conducted between February until May 2023. After passing the triage assessment, the researcher assessed which respondents matched the inclusion and exclusion criteria. The researcher explained the purpose and benefits of the research as well as the procedures that will be passed by the prospective respondent and ask for their consent. The child&#x2019;s anxiety was measured immediately after the intervention. Meanwhile, the companion&#x2019;s anxiety was measured after the child completed the procedure in the emergency room.</p></sec><sec id="s2-6"><title>Data Analysis</title><p>The data were analysed using IBM SPSS Statistics 20, with a significance level of 0.05. Univariate analysis was performed using distribution of frequencies and percentages and mean-standard deviation for categorical and numerical data, respectively. The analysis of the children&#x2019;s anxiety differences between the intervention and control groups used the independent <italic>t</italic> test.</p></sec><sec id="s2-7"><title>Ethical Considerations</title><p>Ethical approval was obtained from the hospital where the study was conducted (Ethical approval number: 017/EC/KEPK-KANDOU/II/2023). Consent was obtained from the accompanying persons and from the children, when possible. No names were provided by the respondents. Following completing the questionnaire, all respondents received a gift of US $2 from the researcher.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><p><xref ref-type="fig" rid="figure1">Figure 1</xref> describes the sampling technique applied. Sixty-six envelopes were provided, half containing a paper labeled &#x201C;intervention&#x201D; and the other half labeled &#x201C;control&#x201D;. Three respondents dropped out due to rejection on completing the questionnaire, making the total number of samples was 63. The participants were 63 school-aged children. Participant characteristics are presented in <xref ref-type="table" rid="table1">Table 1</xref>. Most of the respondents were boys (39/66, 61.9%), had been admitted to the emergency room in the hospital previously (31/63, 49.2%), and were accompanied by their mother (34/63, 54%).</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>CONSORT diagram. VR: virtual reality.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="apinj_v9i1e74900_fig01.png"/></fig><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>Distribution of respondent characteristics.</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="center" valign="bottom">Variable</td><td align="center" valign="bottom">Intervention</td><td align="center" valign="bottom">Control</td><td align="center" valign="bottom">Total</td><td align="center" valign="bottom"><italic>P</italic> value</td></tr></thead><tbody><tr><td align="left" valign="top">Sex, n (%)</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top">.050<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td></tr><tr><td align="left" valign="top">&#x2003;Boy</td><td align="left" valign="top">17 (54.8)</td><td align="left" valign="top">22 (68.8)</td><td align="left" valign="top">39 (61.9)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Girl</td><td align="left" valign="top">14 (45.2)</td><td align="left" valign="top">10 (31.2)</td><td align="left" valign="top">14 (38.1)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">Emergency care experience, n (%)</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top">.614<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td></tr><tr><td align="left" valign="top">&#x2003;Never had experiences</td><td align="left" valign="top">5 (16.1)</td><td align="left" valign="top">6 (18.8)</td><td align="left" valign="top">11 (17.4)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;In the hospital where the research was<break/>&#x2003;conducted</td><td align="left" valign="top">13 (41.9)</td><td align="left" valign="top">18 (56.2)</td><td align="left" valign="top">31 (49.2)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;In another hospital, other than the research<break/>&#x2003;location</td><td align="left" valign="top">8 (25.8)</td><td align="left" valign="top">6 (18.8)</td><td align="left" valign="top">14 (22.3)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" rowspan="2">&#x2003;In the hospital where the research was<break/>&#x2003;conducted and also in another hospital</td><td align="left" valign="top" rowspan="2">5 (16.1)</td><td align="left" valign="top" rowspan="2">2 (6.2)</td><td align="left" valign="top" rowspan="2">7 (11.2)</td><td align="left" valign="top" rowspan="2"/></tr><tr><td align="left" valign="top">Caregiver</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top">.679<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td></tr><tr><td align="left" valign="top">&#x2003;Mother</td><td align="left" valign="top">19 (61.3)</td><td align="left" valign="top">15 (46.9)</td><td align="left" valign="top">34 (54)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Father</td><td align="left" valign="top">1 (3.2)</td><td align="left" valign="top">1 (3.1)</td><td align="left" valign="top">2 (3.2)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Mother and father</td><td align="left" valign="top">7 (22.6)</td><td align="left" valign="top">10 (31.2)</td><td align="left" valign="top">17 (27)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Mother or father and other family</td><td align="left" valign="top">3 (9.7)</td><td align="left" valign="top">6 (18.8)</td><td align="left" valign="top">9 (14.3)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Other family member</td><td align="left" valign="top">1 (3.2)</td><td align="left" valign="top">0 (0)</td><td align="left" valign="top">1 (1.6)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">Caregiver anxiety score, mean (SD)</td><td align="left" valign="top">46.06 (9.413)</td><td align="left" valign="top">54.44 (9.112)</td><td align="left" valign="top"/><td align="left" valign="top">.780<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td></tr></tbody></table><table-wrap-foot><fn id="table1fn1"><p><sup>a</sup>homogeneity test results with the Levene test.</p></fn></table-wrap-foot></table-wrap><p>The children&#x2019;s anxiety in the intervention group (mean 17.71, SD 3.013) was lower than that of the children in the control group (mean 22.31, SD 3.167). There was a significant difference in the anxiety mean scores between the intervention group and the control group <italic>(t</italic><sub>(61)</sub>=<italic>&#x2212;</italic>5.907, <italic>P</italic>&#x003C;.001). The effect size of this study was 4.6 (95% CI 6.161 to 3.045), which were higher than the effect size used as a reference, meaning that the use of VR was significant both from statistical and clinical reasons.</p><p>There was a moderate relationship between caregivers&#x2019;anxiety and school-age children&#x2019;s anxiety (<italic>r</italic>=.532, <italic>P</italic>&#x003C;.001). The mean (SD) caregiver anxiety was 46.06 (9.413) in the intervention group and 54.44 (9.112) in the control group.</p></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>The use of VR could reduce anxiety in school-age children treated in the emergency room (<italic>P</italic>&#x003C;.001). This result coincides with the study involving children undergoing surgery, which found a difference in preoperative anxiety between children who received VR intervention and those who did not (<italic>P</italic>&#x003C;.05) [<xref ref-type="bibr" rid="ref7">7</xref>].</p><p>VR is a diversion method where the child is given tools resembling glasses and headsets to view virtual images from a computer [<xref ref-type="bibr" rid="ref5">5</xref>]. In the era of digital technology, VR can support nurses in implementing nursing care for patients [<xref ref-type="bibr" rid="ref12">12</xref>]. These findings show significant differences in anxiety between the control and intervention groups. The mean score of the intervention group was lower than that of the control group. The children who received the VR intervention focused on the video they were watching [<xref ref-type="bibr" rid="ref5">5</xref>]. Watching video using VR involves more than one sense, namely, vision and hearing. This made the use of VR more attractive to the children&#x2019;s attention compared to distraction techniques that only involved one sense, such as music (hearing) or picture books (vision) [<xref ref-type="bibr" rid="ref8">8</xref>]. The children enjoyed the video presented using VR; therefore, their anxiety was reduced.</p><p>There was a moderate relationship between caregivers&#x2019;anxiety and school-age children&#x2019;s anxiety (<italic>r</italic>=.532, <italic>P</italic>&#x003C;.001). The presence of parents can be a source of motivation and strengthen children [<xref ref-type="bibr" rid="ref9">9</xref>]. Parents&#x2019; anxiety is related to children&#x2019;s anxiety [<xref ref-type="bibr" rid="ref10">10</xref>]. When the child&#x2019;s anxiety decreased, the parent&#x2019;s anxiety also decreased.</p></sec><sec id="s4-2"><title>Limitations</title><p>This study did not measure the anxiety score before the intervention due to permission granted from the research location. The anxiety measurement before the intervention would delay the treatment that the patient would receive. Apart from that, the intervention was only given for 10 minutes, so the researchers were concerned that giving questionnaires twice, both for children and caregivers, in a short time interval could cause discomfort.</p></sec><sec id="s4-3"><title>Conclusions</title><p>The findings of this study show that the use of VR could reduce anxiety in school-age children treated in the emergency room. Therefore, the authors recommend that hospital management establish a policy related to the use of VR in managing children&#x2019;s anxiety.</p></sec></sec></body><back><ack><p>The authors thank the Ministry of Health of Republic of Indonesia for supporting the first author&#x2019;s study period and Universitas Indonesia for publication funding through PUTI Pascasarjana Grant 2023 and acknowledge respondents who participated in this study.</p></ack><fn-group><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">CSAS-C</term><def><p>Chinese version of the State Anxiety Scale for Children</p></def></def-item><def-item><term id="abb2">SAI</term><def><p>State Anxiety Inventory</p></def></def-item><def-item><term id="abb3">VR</term><def><p>virtual reality</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="book"><person-group person-group-type="author"><name name-style="western"><surname>Hockenberry</surname><given-names>MJ</given-names> </name><name name-style="western"><surname>Rodgers</surname><given-names>CC</given-names> </name><name name-style="western"><surname>Wilson</surname><given-names>DM</given-names> </name></person-group><source>Wong&#x2019;s Essential of Pediatric Nursing</source><year>2017</year><access-date>2025-08-05</access-date><edition>10</edition><publisher-name>Elsevier Inc</publisher-name><comment><ext-link ext-link-type="uri" xlink:href="https://repository.poltekkes-kaltim.ac.id/638/1/Wong%E2%80%99s%20Essentials%20of%20Pediatric%20Nursing%20by%20Marilyn%20J.%20Hockenberry%20Cheryl%20C.%20Rodgers%20David%20M.%20Wilson%20(z-lib.org).pdf">https://repository.poltekkes-kaltim.ac.id/638/1/Wong%E2%80%99s%20Essentials%20of%20Pediatric%20Nursing%20by%20Marilyn%20J.%20Hockenberry%20Cheryl%20C.%20Rodgers%20David%20M.%20Wilson%20(z-lib.org).pdf</ext-link></comment></nlm-citation></ref><ref id="ref2"><label>2</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Giarelli</surname><given-names>E</given-names> </name><name name-style="western"><surname>Nocera</surname><given-names>R</given-names> </name><name name-style="western"><surname>Turchi</surname><given-names>R</given-names> </name><name name-style="western"><surname>Hardie</surname><given-names>TL</given-names> </name><name name-style="western"><surname>Pagano</surname><given-names>R</given-names> </name><name name-style="western"><surname>Yuan</surname><given-names>C</given-names> </name></person-group><article-title>Sensory stimuli as obstacles to emergency care for children with autism spectrum disorder</article-title><source>Adv Emerg Nurs J</source><year>2014</year><volume>36</volume><issue>2</issue><fpage>145</fpage><lpage>163</lpage><pub-id pub-id-type="doi">10.1097/TME.0000000000000013</pub-id><pub-id pub-id-type="medline">24785668</pub-id></nlm-citation></ref><ref id="ref3"><label>3</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Pragholapati</surname><given-names>A</given-names> </name><name name-style="western"><surname>Sarinengsih</surname><given-names>Y</given-names> </name></person-group><article-title>Tingkat kecemasan pada pasien anak usia sekolah (6-12 tahun) di ruang igd rsud majalaya kabupaten bandung. 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